2025 (Gotham FC / Fort Lauderdale United FC): Made her NWSL debut for Gotham FC on April 19. Loaned to Fort Lauderdale United FC in the Gainbridge Super League on Aug. 28. Scored her first goal for Fort Lauderdale on Sept. 28 with a free kick.
2021–24 (Dreamz Ladies FC): Began her career in Ghana with Dreamz Ladies FC. In 2024, she was nominated for the CAF Young Player of the Year award.
Nyamekye made her senior national team debut in 2023, appearing in a 3-0 victory over Benin on Feb. 19. She went on to captain Ghana’s U-20 Women’s National Team at the 2024 FIFA U-20 Women’s World Cup, starting all three group-stage matches and finishing the tournament with two goals, one assist and a team-leading 22 attempts on goal. In 2025, she helped Ghana secure a bronze medal at WAFCON, defeating South Africa in the third-place match.
